2,2',5-PCB

Names

[ CAS No. ]:
37680-65-2

[ Name ]:
2,2',5-PCB

[Synonym ]:
2,2',5-PCB
2,2',5-Trichlorobiphenyl
1,1'-Biphenyl, 2,2',5-trichloro-
1,4-dichloro-2-(2-chlorophenyl)benzene

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
317.6±27.0 °C at 760 mmHg

[ Melting Point ]:
43-44ºC

[ Molecular Formula ]:
C₁₂H₇Cl₃

[ Molecular Weight ]:
257.543

[ Flash Point ]:
216.1±19.3 °C

[ Exact Mass ]:
255.961334

[ LogP ]:
5.43

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.604

[ Storage condition ]:
room temp

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DV8820000

CHEMICAL NAME :: 1,1'-Biphenyl, 2,2',5-trichloro-

CAS REGISTRY NUMBER :: 37680-65-2

LAST UPDATED :: 199710

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H7-Cl3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 150 mg/kg/3D-I

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other hydrolases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 33,94,1975

Safety Information

[ Symbol ]:

GHS08, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H373-H410

[ Precautionary Statements ]:
P273-P391-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
N,Xn

[ Risk Phrases ]:
33-50/53

[ Safety Phrases ]:
35-60-61

[ RIDADR ]:
UN 3432 9/PG 2

[ RTECS ]:
DV8820000

[ HS Code ]:
2903999090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Alteration of regiospecificity in biphenyl dioxygenase by active-site engineering.

J. Bacteriol. 184(13) , 3682-8, (2002)

Biphenyl dioxygenase (Bph Dox) is responsible for the initial dioxygenation step during the metabolism of biphenyl. The large subunit (BphA1) of Bph Dox plays a crucial role in the determination of th...

Dihydroxylation and dechlorination of chlorinated biphenyls by purified biphenyl 2,3-dioxygenase from Pseudomonas sp. strain LB400.

J. Bacteriol. 177(1) , 20-6, (1995)

Oxidation of biphenyl and nine chlorinated biphenyls (CBs) by the biphenyl 2,3-dioxygenase from Pseudomonas sp. strain LB400 was examined. The purified terminal oxygenase required the addition of part...

Uterotropic and enzyme induction effects of 2,2',5-trichlorobiphenyl.

Bull. Environ. Contam. Toxicol. 54(4) , 494-500, (1995)