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Propyperone

Names

[ CAS No. ]:
3781-28-0

[ Name ]:
Propyperone

[Synonym ]:
R 4082
Floropipeton
Propiperona [INN-Spanish]
1-<3-(4-Fluor-benzoyl)-propyl>-4-piperidino-4-propionyl-piperidin
Propyperonum [INN-Latin]
Propyperone
4'-Fluoro-4-(4-piperidino-4-propionylpiperidino)butyrophenone
BUTYROPHENONE,4'-FLUORO-4-(4-PIPERIDINO-4-PROPIONYLPIPERIDINO)
1-(4-fluoro-phenyl)-4-(4'-propionyl-octahydro-[1,4']bipyridinyl-1'-yl)-butan-1-one
Propiperona

Chemical & Physical Properties

[ Density]:
1.112g/cm3

[ Boiling Point ]:
515.6ºC at 760mmHg

[ Molecular Formula ]:
C23H33FN2O2

[ Molecular Weight ]:
388.51900

[ Flash Point ]:
265.7ºC

[ Exact Mass ]:
388.25300

[ PSA ]:
40.62000

[ LogP ]:
3.96400

[ Index of Refraction ]:
1.534

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EU4375000
CHEMICAL NAME :
Butyrophenone, 4'-fluoro-4-(4-piperidino-4-propionylpiperidino)-
CAS REGISTRY NUMBER :
3781-28-0
BEILSTEIN REFERENCE NO. :
0495940
LAST UPDATED :
199712
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C23-H33-F-N2-O2
MOLECULAR WEIGHT :
388.58
WISWESSER LINE NOTATION :
T6NTJ A- DT6NTJ A3VR DF& DV2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,192,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,192,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
275 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,192,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
420 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,192,1972

Safety Information

[ HS Code ]:
2933399090

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds