α-Fluoro-β-alanine

[ Density]:
1.302g/cm3

[ Boiling Point ]:
264.5ºC at 760 mmHg

[ Melting Point ]:
222ºC

[ Molecular Formula ]:
C₃H₆FNO₂

[ Molecular Weight ]:
107.08400

[ Flash Point ]:
113.8ºC

[ Exact Mass ]:
107.03800

[ PSA ]:
63.32000

[ LogP ]:
0.06810

[ Index of Refraction ]:
1.428

Click to get detail MSDS

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2922499990

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

beta-alanine and alpha-fluoro-beta-alanine concentrative transport in rat hepatocytes is mediated by GABA transporter GAT-2.

Am. J. Physiol. 276(1 Pt 1) , G206-10, (1999)

Studies on the compartmentalization of uridine catabolic metabolism in liver have indicated accumulation of beta-alanine as well as alpha-fluoro-beta-alanine (FbetaAL) for 5-fluorouracil in the hepato...

Proton-decoupled 19F spectroscopy of 5-FU catabolites in human liver.

Magn. Reson. Med. 37(3) , 321-6, (1997)

An RF network and a dual-tuned surface coil are described for obtaining proton-decoupled, NOE enhanced 19F spectra from a whole body clinical imager operating at 1.5 Tesia. The network removes 19F fre...

The achievement of mass balance by simultaneous quantification of floxuridine prodrug, floxuridine, 5-fluorouracil, 5-dihydrouracil, α-fluoro-β-ureidopropionate, α-fluoro-β-alanine using LC-MS.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(13-14) , 915-20, (2011)

5-Fluoro-2'-deoxyuridine (floxuridine, 5-FdUrd) and 5-fluorouracil (5-FU) are widely used for the treatment of colorectal cancers. The mechanisms of action of 5-FdUrd and 5-FU, as well as the biochemi...

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