Methyl 3-(dimethylamino)propanoate

Names

[ CAS No. ]:
3853-06-3

[ Name ]:
Methyl 3-(dimethylamino)propanoate

[Synonym ]:
methyl 3-(dimethylamino)propanoate
Methyl 3-(dimethylamino)propionate
MFCD00009643

Chemical & Physical Properties

[ Density]:
0.948g/cm3

[ Boiling Point ]:
149.1ºC at 760mmHg

[ Molecular Formula ]:
C₆H₁₃NO₂

[ Molecular Weight ]:
131.17300

[ Flash Point ]:
51.1ºC

[ Exact Mass ]:
131.09500

[ PSA ]:
29.54000

[ LogP ]:
0.11110

[ Index of Refraction ]:
n20/D 1.418(lit.)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY5992870

CHEMICAL NAME :: beta-Alanine, N,N-dimethyl-, methyl ester

CAS REGISTRY NUMBER :: 3853-06-3

LAST UPDATED :: 199112

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H13-N-O2

MOLECULAR WEIGHT :: 131.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 34,345,1968

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
10-36/37/38

[ Safety Phrases ]:
16-26-36/37/39

[ RIDADR ]:
UN 3272 3/PG 3

[ RTECS ]:
AY5992870

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

β-Amino ester enolate as an acrylate anion equivalent for the synthesis of. α.-methylene esters, acids, and lactones.

J. Org. Chem. 46(22) , 4536-4541, (1981)