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Tripdiolide

Names

[ CAS No. ]:
38647-10-8

[ Name ]:
Tripdiolide

[Synonym ]:
Tri-p-cumylphosphin
triptodiolide
Phosphine,tris(4-(1-methylethyl)phenyl)
(3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS,10S)-6,10-Dihydroxy-6a-isopropyl-8b-methyl-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydrotrisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3H)-one
Trisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6,10-dihydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS,10S)-
Tripdiolide
Tri-(p-isopropylphenyl)phosphin

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
656.4±55.0 °C at 760 mmHg

[ Melting Point ]:
226-228ºC

[ Molecular Formula ]:
C20H24O7

[ Molecular Weight ]:
376.400

[ Flash Point ]:
240.5±25.0 °C

[ Exact Mass ]:
376.152191

[ PSA ]:
104.35000

[ LogP ]:
0.17

[ Vapour Pressure ]:
0.0±4.5 mmHg at 25°C

[ Index of Refraction ]:
1.669

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YK7751500
CHEMICAL NAME :
Triptolide, 2-hydroxy-, (2-beta)-
CAS REGISTRY NUMBER :
38647-10-8
LAST UPDATED :
198605
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H24-O7

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
889 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2942000000

Customs

[ HS Code ]: 2942000000


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