2-METHOXY-5-NITROBENZYL BROMIDE

Names

[ CAS No. ]:
3913-23-3

[ Name ]:
2-METHOXY-5-NITROBENZYL BROMIDE

[Synonym ]:
2-(bromomethyl)-1-methoxy-4-nitrobenzene
MFCD00007329
EINECS 223-471-6
2-METHOXY-5-NITROBENZYL BROMIDE

Chemical & Physical Properties

[ Density]:
1.589g/cm3

[ Boiling Point ]:
348.7ºC at 760 mmHg

[ Melting Point ]:
76-78ºC(lit.)

[ Molecular Formula ]:
C₈H₈BrNO₃

[ Molecular Weight ]:
246.05800

[ Flash Point ]:
164.7ºC

[ Exact Mass ]:
244.96900

[ PSA ]:
55.05000

[ LogP ]:
3.02150

[ Index of Refraction ]:
1.588

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XS7966500

CHEMICAL NAME :: Toluene, alpha-bromo-2-methoxy-6-nitro-

CAS REGISTRY NUMBER :: 3913-23-3

BEILSTEIN REFERENCE NO. :: 1878596

LAST UPDATED :: 199707

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H8-Br-N-O3

MOLECULAR WEIGHT :: 246.08

WISWESSER LINE NOTATION :: WNR DO1 C1E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 20 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S27-S45-S36-S37-S39

[ RIDADR ]:
UN 3261 8/PG 2

[ Packaging Group ]:
III

[ HS Code ]:
2909309090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Chemical modification of mouse interferons.

J. Interferon Res. 2(2) , 177-85, (1982)

Mouse interferon (MuIFN) preparations containing both the alpha and beta species were treated with chemical modifying reagents specific for lysine, cysteine and tryptophan residues. The purpose was to...

Mechanism-based inactivation of rat liver cytochrome P-450 2B1 by 2-methoxy-5-nitrobenzyl bromide.

Drug Metab. Dispos. 27(6) , 741-5, (1999)

Mechanism-based inactivators serve as probes of enzyme mechanism, function, and structure. Koshland's Reagent II (2-methoxy-5-nitrobenzyl bromide, KR-II) is a potential mechanism-based inactivator of ...

[Comparison of auc values for caffeine and its metabolites after single and repeated administration of 2-methoxy-5-nitrobenzyl bromide].

Rocz. Panstw. Zakl. Hig. 54 Suppl , 56, (2003)