[(2R,5R)-2-[[(6E,8E,10E,12E,14E,16E,18E)-4,22,24,28,29,34,36-heptahydroxy-23-methoxycarbonyl-2,3,5-trimethyl-26,32,38-trioxo-1-oxacyclooctatriaconta-6,8,10,12,14,16,18-heptaen-20-yl]oxy]-3,5-dihydroxy-6-methyloxan-4-yl]azanium,chloride
Names
[ CAS No. ]:
39387-88-7
[ Name ]:
[(2R,5R)-2-[[(6E,8E,10E,12E,14E,16E,18E)-4,22,24,28,29,34,36-heptahydroxy-23-methoxycarbonyl-2,3,5-trimethyl-26,32,38-trioxo-1-oxacyclooctatriaconta-6,8,10,12,14,16,18-heptaen-20-yl]oxy]-3,5-dihydroxy-6-methyloxan-4-yl]azanium,chloride
[Synonym ]:
Amphotericin B,8,9-dideoxy-10-hydroxy-7-oxo-,methyl ester,hydrochloride
Candidine,methyl ester,hydrochloride
Chemical & Physical Properties
[ Molecular Formula ]:
C48H74ClNO17
[ Molecular Weight ]:
972.55100
[ Exact Mass ]:
971.46500
[ PSA ]:
313.29000
[ LogP ]:
2.35320
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EX4700000
- CHEMICAL NAME :
- Candidin, methyl ester, hydrochloride
- CAS REGISTRY NUMBER :
- 39387-88-7
- LAST UPDATED :
- 198909
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C48-H73-N-O17.Cl-H
- MOLECULAR WEIGHT :
- 972.68
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 25,261,1972