5-Hydroxyanthranilic acid

Names

[ CAS No. ]:
394-31-0

[ Name ]:
5-Hydroxyanthranilic acid

[Synonym ]:
5-Hydroxyanthranilic
5-hydroxy-2-aminobenzoic acid
2-Amino-5-Hydroxybenzoic
5-hydroxy-2-anthranilic acid
diabeton
5-HYDROXYANTHRANILLIC ACID
MFCD00007870
4-aminophenol-2-carboxylic acid
2-AMINO-5-HYDROXYBENZOIC ACID
Glyklaside
Hydroxyanthranilic acid

Biological Activity

[Description]:

2-Amino-5-hydroxybenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Diabeton 是一种磺酰脲类降血糖药，口服用于治疗非胰岛素依赖型糖尿病。当这种改变本身未被证明有效时，它用于通过饮食改变来补充治疗。它的作用持续时间为12小时或更长时间。老年患者可用糖尿病代替氯磺丙脲。

Chemical & Physical Properties

[ Density]:
1.491 g/cm3

[ Boiling Point ]:
417.8ºC at 760 mmHg

[ Melting Point ]:
247 °C (dec.)(lit.)

[ Molecular Formula ]:
C₇H₇NO₃

[ Molecular Weight ]:
153.14

[ Flash Point ]:
206.5ºC

[ Exact Mass ]:
153.04300

[ PSA ]:
83.55000

[ LogP ]:
1.25380

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/22;R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918290000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Chromatographic evaluation and QSAR optimization for benzoic acid analogues against carbonic anhydrase III.

J. Enzyme Inhib. Med. Chem. 30 , 420-9, (2015)

An HPLC-size exclusion method was developed as an assay method to evaluate the binding of tested compounds with carbonic anhydrase III (CAIII) enzyme. Inhibition of CAIII by a group of benzoic acid an...

[The effect of diabeton and metformin on the free-radical oxidation processes and the structural characteristics of the phospholipid composition of the erythrocyte membranes in non-insulin-dependent diabetes mellitus].

Sov. Med. (7) , 14-6, (1991)

Newly detected noninsulin--dependent diabetes mellitus is shown to have changes in phospholipid structure of erythrocytic membranes: a fall in total phospholipids, sphingomyelin, phosphatidylcholine, ...

[The efficacy of the antiaggregants ticlid and diabeton in correcting chronic intravascular microcoagulation of the blood in diabetic patients].

Ter. Arkh. 63(10) , 44-9, (1991)

Hemocoagulation was examined in 477 diabetes mellitus patients. Whatever the disease type, severity, duration and the intensity of microvascular complications, diabetes mellitus was discovered to be m...