4-(4-Chlorophenyl)-4-piperidinol
Names
[ CAS No. ]:
39512-49-7
[ Name ]:
4-(4-Chlorophenyl)-4-piperidinol
[Synonym ]:
4-Piperidinol, 4-(4-chlorophenyl)-
4-(p-Chlorophenyl)-4-piperidinol
Haloperidol metabolite I
4-(4-Chlorophenyl)-4-piperidinol
4-(4-Chlorophenyl)piperidin-4-ol
4-Hydroxy-4-(p-chlorophenyl)piperidine
EINECS 254-479-8
4-(para-Chlorophenyl)-4-hydroxypiperidine
4-(p-Chlorophenyl)-4-hydroxypiperidine
MFCD00006001
4-(4-Chlorophenyl)-4-hydroxypiperidine,crystalline
4-p-Chlorophenyl-4-piperidinol
4-p-chlorophenyl-4-hydroxypiperidine
4-(4-Chlorophenyl)-4-hydroxypiperidine
4-Piperidinol, 4- (4-chlorophenyl)-
4-Hydroxy-4-(4-chlorophenyl)piperidine
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
344.5±42.0 °C at 760 mmHg
[ Melting Point ]:
137-140 °C(lit.)
[ Molecular Formula ]:
C11H14ClNO
[ Molecular Weight ]:
211.688
[ Flash Point ]:
162.1±27.9 °C
[ Exact Mass ]:
211.076385
[ PSA ]:
32.26000
[ LogP ]:
1.78
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.572
[ Storage condition ]:
Refrigerator
[ Water Solubility ]:
340 mg/L (20 ºC)
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
29333999
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29333999
Articles
Psychopharmacology 205 , 21-33, (2009)
We evaluated the effects of haloperidol and its metabolites on capsaicin-induced mechanical hypersensitivity (allodynia) and on nociceptive pain induced by punctate mechanical stimuli in mice.Subcutan...
In-vitro characterization of the cytochrome P450 isoenzymes involved in the back oxidation and N-dealkylation of reduced haloperidol.Pharmacogenetics 8(5) , 383-9, (1998)
In-vitro studies were performed using human liver microsomes and c-DNA-expressed human P450 isoforms to identify the cytochrome P450 isoenzyme(s) involved in the back oxidation and N-dealkylation of r...
Comparison of SSI with APCI as an interface of HPLC-mass spectrometry for analysis of a drug and its metabolites.J. Am. Soc. Mass Spectrom. 13(3) , 204-8, (2002)
Sonic spray ionization (SSI) was compared with atmospheric pressure chemical ionization (APCI) as an interface of high-performance liquid chromatography (HPLC)-mass spectrometry (MS) for sensitive ana...