Thiazole-4-carboxylic acid

Names

[ Name ]:
Thiazole-4-carboxylic acid

[Synonym ]:
Thiazole-4-carboxylic acid
4-Thiazolecarboxylic acid
4-Thiazolecarboxylicacid
MFCD00623589
1,3-Thiazole-4-carboxylic acid
Thiazole-4-carboxylicacid

Biological Activity

[Description]:

4-Thiazolecarboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
319.2±15.0 °C at 760 mmHg

[ Melting Point ]:
195-199 °C(lit.)

[ Molecular Formula ]:
C₄H₃NO₂S

[ Molecular Weight ]:
129.14

[ Flash Point ]:
146.9±20.4 °C

[ Exact Mass ]:
128.988449

[ PSA ]:
78.43000

[ LogP ]:
1.06

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.618

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R43

[ Safety Phrases ]:
S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Aryl hydrocarbon receptor (AhR) attenuation of subchronic cigarette smoke-induced pulmonary neutrophilia is associated with retention of nuclear RelB and suppression of intercellular adhesion molecule-1 (ICAM-1).

Toxicol. Sci. 140(1) , 204-23, (2014)

Cigarette smoke is associated with chronic and enhanced pulmonary inflammation characterized by increased cytokine production and leukocyte recruitment to the lung. Although the aryl hydrocarbon recep...

Establishment of a stable aryl hydrocarbon receptor-responsive HepG2 cell line.

Cytotechnology 67 , 621-32, (2015)

The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor. It heterodimerizes with aryl hydrocarbon nuclear translocator, binds to the xenobiotic-responsive element (XRE), and enh...