5-Fluoroindole

Names

[ CAS No. ]:
399-52-0

[ Name ]:
5-Fluoroindole

[Synonym ]:
MFCD00005671
1H-Indole, 5-fluoro-
5-Fluoro-1H-indole
5-Fluoroindole
5-Fluoro indole
EINECS 206-917-4

Biological Activity

[Description]:

5-Fluoroindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
258.0±13.0 °C at 760 mmHg

[ Melting Point ]:
45-48 °C(lit.)

[ Molecular Formula ]:
C₈H₆FN

[ Molecular Weight ]:
135.14

[ Flash Point ]:
109.9±19.8 °C

[ Exact Mass ]:
135.048431

[ PSA ]:
15.79000

[ LogP ]:
2.28

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.646

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Ionization potentials of fluoroindoles and the origin of nonexponential tryptophan fluorescence decay in proteins.

J. Am. Chem. Soc. 127(11) , 4104-13, (2005)

This work reports an explanation for the unusual monoexponential fluorescence decay of 5-fluorotryptophan (5FTrp) in single-Trp mutant proteins [Broos, J.; Maddalena, F.; Hesp, B. H. J. Am. Chem. Soc....

Regulation of tryptophan synthase gene expression in Chlamydia trachomatis.

Mol. Microbiol. 49(5) , 1347-59, (2003)

We previously reported that Chlamydia trachomatis expresses the genes encoding tryptophan synthase (trpA and trpB). The results presented here indicate that C. trachomatis also expresses the tryptopha...

Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.

J. Med. Chem. 52 , 4694-715, (2009)

We describe a novel fragment library termed fragments of life (FOL) for structure-based drug discovery. The FOL library includes natural small molecules of life, derivatives thereof, and biaryl protei...