2-Amino-4-chloropyrimidine

Names

[ Name ]:
2-Amino-4-chloropyrimidine

[Synonym ]:
2-amine-4-chloropyrimidine
2-Pyrimidinamine, 4-chloro-
4-Chloropyrimidin-2-Amine
2-Amino-4-chlor-pyrimidin
2-amino-4-chloropyrimidein
MFCD00038021
4-chloro-2-aminopyrimidine
2-amino-4-chloro-pyrimidine
2-Amino-4-chloropyrimidine
4-Chloro-2-pyrimidinamine
4-chlorpyrimidin-2-amin
CHLORO-ISO-CYTOSINE

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
314.6±34.0 °C at 760 mmHg

[ Melting Point ]:
155-160ºC (dec.)

[ Molecular Formula ]:
C₄H₄ClN₃

[ Molecular Weight ]:
129.548

[ Flash Point ]:
144.1±25.7 °C

[ Exact Mass ]:
129.009369

[ PSA ]:
51.80000

[ LogP ]:
0.58

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.618

[ Storage condition ]:
-20°C Freezer, Under Inert Atmosphere

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R37/38;R41

[ Safety Phrases ]:
S26-S36/39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Mild and general methods for the palladium-catalyzed cyanation of aryl and heteroaryl chlorides.

Org. Lett. 9 , 1711, (2007)

[reaction: see text] New methods for the palladium-catalyzed cyanation of aryl and heteroaryl chlorides have been developed, featuring sterically demanding, electron-rich phosphines. Highly challengin...