Indole-15N

Names

[ CAS No. ]:
40167-58-6

[ Name ]:
Indole-15N

Biological Activity

[Description]:

Indole-15N is the 15N labeled Indole[1]. Indole is an endogenous metabolite.

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Molecular Formula ]:
C8H7N

[ Molecular Weight ]:
118.14100

[ Exact Mass ]:
118.05500

[ PSA ]:
15.79000

[ LogP ]:
2.16790

Safety Information

[ Symbol ]:

GHS05, GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H311-H315-H318-H335-H400

[ Precautionary Statements ]:
P261-P273-P280-P305 + P351 + P338-P312

[ RIDADR ]:
UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all

Related Compounds