TMC-205

Names

[ Name ]:
TMC-205

[Synonym ]:
1H-Indole-3-carboxylic acid,6-[(1E)-3-methyl-1,3-butadienyl]

Biological Activity

[Description]:

TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Microbial Metabolite

[References]

[1]. Gao Y, et al. Total Synthesis and Biological Studies of TMC-205 and Analogues as Anticancer Agents and Activators of SV40 Promoter. ACS Med Chem Lett. 2014;5(8):863-867. Published 2014 Jun 23.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₃NO₂

[ Molecular Weight ]:
227.25900

[ Exact Mass ]:
227.09500

[ PSA ]:
53.09000

[ LogP ]:
3.45540

TMC-205

Names

Biological Activity

Chemical & Physical Properties

Related Compounds