4-Fluorophenylacetic acid

Names

[ CAS No. ]:
405-50-5

[ Name ]:
4-Fluorophenylacetic acid

[Synonym ]:
2-(4-fluorophenyl)acetic acid
4-Fluorophenylacetic acid
EINECS 206-972-4
Benzeneacetic acid, 4-fluoro-
(4-Fluorophenyl)acetic acid
MFCD00004343

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
265.3±15.0 °C at 760 mmHg

[ Melting Point ]:
81-83 °C(lit.)

[ Molecular Formula ]:
C₈H₇FO₂

[ Molecular Weight ]:
154.138

[ Flash Point ]:
114.3±20.4 °C

[ Exact Mass ]:
154.043015

[ PSA ]:
37.30000

[ LogP ]:
1.56

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.529

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Transfer of parahydrogen-induced hyperpolarization to 19F.

J. Phys. Chem. A 110(10) , 3521-6, (2006)

Homogeneous hydrogenations of unsaturated substrates with parahydrogen yield strong NMR signal enhancements of the transferred 1H nuclei if the symmetry of H2 is broken in the resulting hydrogenated p...

Investigations into tumor accumulation and peroxisome proliferator activated receptor binding by F-18 and C-11 fatty acids.

Nucl. Med. Biol. 29(2) , 211-6, (2002)

[11C]Acetate, a myocardial PET imaging agent for analysis of oxidative metabolism, has potential use in tumor imaging. Aromatic fatty acids display antitumor effects with phenylacetate currently in cl...

Chromatographic selectivity study of 4-fluorophenylacetic acid positional isomers separation.

J. Chromatogr. A. 1156(1-2) , 25-34, (2007)

Unique properties of the fluorine atom stimulate widespread use and development of new organofluorine compounds in agrochemistry, biotechnology and pharmacology applications. However, relatively few s...