DICHLORO(4,5-DIMETHYL-o-PHENYLENE-DIAMMINE)PLATINUM(II)
Names
[ CAS No. ]:
40580-75-4
[ Name ]:
DICHLORO(4,5-DIMETHYL-o-PHENYLENE-DIAMMINE)PLATINUM(II)
Chemical & Physical Properties
[ Boiling Point ]:
279.6ºC at 760 mmHg
[ Molecular Formula ]:
C8H10Cl2N2Pt
[ Molecular Weight ]:
400.16200
[ Flash Point ]:
144.9ºC
[ Exact Mass ]:
398.98700
[ PSA ]:
24.06000
[ LogP ]:
3.70830
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TP2494900
- CHEMICAL NAME :
- Platinum(II), dichloro(4,5-dimethyl-o-phenylenediammine)-, (SP-4-2)-
- CAS REGISTRY NUMBER :
- 40580-75-4
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C8-H12-Cl2-N2-Pt
- MOLECULAR WEIGHT :
- 402.21
- WISWESSER LINE NOTATION :
- ZR BZ D1 E1 &G-PT-G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 283 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes Tumorigenic - active as anti-cancer agent
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 10200 nmol/L
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,459,1980