2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy-8-(morpholinomethyl)-, 21-acetate
Names
[ CAS No. ]:
4075-43-8
[ Name ]:
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy-8-(morpholinomethyl)-, 21-acetate
[Synonym ]:
PF-49
NCI 144-143
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione,5,6,9,17,19,21-hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy-8-(morpholinomethyl)-,21-acetate
Chemical & Physical Properties
[ Density]:
1.35g/cm3
[ Boiling Point ]:
907.6ºC at 760 mmHg
[ Molecular Formula ]:
C42H56N2O13
[ Molecular Weight ]:
796.90000
[ Flash Point ]:
502.7ºC
[ Exact Mass ]:
796.37800
[ PSA ]:
213.78000
[ LogP ]:
4.66220
[ Index of Refraction ]:
1.634
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KD1920700
- CHEMICAL NAME :
- 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy -8-(morpholinomethyl) -, 21-acetate
- CAS REGISTRY NUMBER :
- 4075-43-8
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C42-H56-N2-O13
- MOLECULAR WEIGHT :
- 797.00
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 188 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,531,1977