Nonylbenzene-PEG8-OH

Names

[ Name ]:
Nonylbenzene-PEG8-OH

[Synonym ]:
2-[2-(2-{2-[2-(2-{2-[2-(4-Nonyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethanol
nonylphenol ethoxylate
nonylphenyl ethoxyle
Igepal BC8

Biological Activity

[Description]:

Nonylbenzene-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₅₆O₉

[ Molecular Weight ]:
572.77100

[ Exact Mass ]:
572.39200

[ PSA ]:
94.07000

[ LogP ]:
4.46700

Nonylbenzene-PEG8-OH

Names

Biological Activity

Chemical & Physical Properties

Related Compounds