STX-213
Names
[ CAS No. ]:
415974-72-0
[ Name ]:
STX-213
Biological Activity
[Description]:
An orally active, second-generation steroid sulfatase inhibitor with IC50 of 0.5 nM; completely inhibits liver and tumor STS activity, and fully inhibits growth of MCF-7STS tumors in vivo.
[References]
References 1. Foster PA, et al. Clin Cancer Res. 2006 Sep 15;12(18):5543-9. 2. Foster PA, et al. Breast Cancer Res Treat. 2008 Sep;111(1):129-38. 3. Foster PA, et al. Endocrinology. 2008 Aug;149(8):4035-42. 4. Foster PA, et al. Clin Cancer Res. 2008 Oct 15;14(20):6469-77. View Related Products by Target Steroid Sulfatase (STS)
Chemical & Physical Properties
[ Molecular Formula ]:
C21H28N2O5S
[ Molecular Weight ]:
420.524