Methyl 8-chloro-8-oxooctanoate

Names

[ Name ]:
Methyl 8-chloro-8-oxooctanoate

[Synonym ]:
methyl 8-chloro-8-oxo-octanoate
MFCD00134649
metyl 8-chloro-8-oxooctanoate
Methyl suberyl chloride
7-chlorocarbonylheptanoic acid methyl ester
7-carbomethoxyheptanoyl chloride
suberyl chloride methyl ester
methyl 7-(chloroformyl)-heptanoate

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₅ClO₃

[ Molecular Weight ]:
206.66700

[ Exact Mass ]:
206.07100

[ PSA ]:
43.37000

[ LogP ]:
2.26540

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Risk Phrases ]:
34

[ Safety Phrases ]:
23-26-27-36/37/39-45

[ RIDADR ]:
UN 3265 8/PG 2

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Synthesis and Biological Evaluation of JAHAs: Ferrocene-Based Histone Deacetylase Inhibitors.

ACS Med. Chem. Lett. 2(5) , 358-362, (2011)

N(1)-Hydroxy-N(8)-ferrocenyloctanediamide, JAHA (7), an organometallic analogue of SAHA containing a ferrocenyl group as a phenyl bioisostere, displays nanomolar inhibition of class I HDACs, excellent...

8-cyclopentadienyltricarbonyl 99mtc 8-oxooctanoic acid: a novel radiotracer for evaluation of medium chain fatty acid metabolism in the liver.

Bioconjug. Chem. 15(1) , 121-7, (2004)

8-Cyclopentadienyltricarbonyl 99mTc 8-oxooctanoic acid (99mTc-CpTTOA; 1a) was synthesized for evaluation of medium chain fatty acid metabolism in the liver. 99mTc-CpTTOA was prepared in high radiochem...

High-performance liquid chromatographic assay with fluorescence detection for the evaluation of inhibitors against fatty acid amide hydrolase.

Anal. Bioanal. Chem 394(6) , 1679-1685, (2009)

A fluorescent assay for the evaluation of inhibitors of fatty acid amide hydrolase (FAAH) is described. Microsomes from rat brain served as enzyme source. N-(2-Hydroxyethyl)-4-pyren-1-ylbutanamide was...