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Koaburaside

Names

[ CAS No. ]:
41653-73-0

[ Name ]:
Koaburaside

[Synonym ]:
Koaburaside
4-Hydroxy-3,5-dimethoxyphenyl Beta-D-glucopyranoside
β-D-Glucopyranoside, 4-hydroxy-3,5-dimethoxyphenyl
4-Hydroxy-3,5-dimethoxyphenyl β-D-glucopyranoside

Biological Activity

[Description]:

Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC50 of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Cancer
Research Areas >> Infection
Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Research Areas >> Inflammation/Immunology

[References]

[1]. He Y, et al. Phenolic compounds from Eurycorymbus cavaleriei. J Asian Nat Prod Res. 2011 Jun;13(6):575-80.  

[2]. Subedi L, et al. Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro. Phytomedicine. 2016 Jul 15;23(8):872-81.  

[3]. Choi HG, et al. Phenolic glycosides from Lindera obtusiloba and their anti-allergic inflammatory activities. Nat Prod Commun. 2013 Feb;8(2):181-2.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
599.0±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C14H20O9

[ Molecular Weight ]:
332.303

[ Flash Point ]:
316.1±30.1 °C

[ Exact Mass ]:
332.110718

[ PSA ]:
138.07000

[ LogP ]:
-1.60

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.609

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds