1,1,1-Trifluoroacetone
Names
[ CAS No. ]:
421-50-1
[ Name ]:
1,1,1-Trifluoroacetone
[Synonym ]:
1,1,1-Trifluorpropan-2-on
EINECS 207-005-9
1,1,1-Trifluoroacetone
2-Propanone, 1,1,1-trifluoro-
MFCD00000423
1,1,1-trifluoropropan-2-one
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
21.5±0.0 °C at 760 mmHg
[ Melting Point ]:
-78 °C
[ Molecular Formula ]:
C3H3F3O
[ Molecular Weight ]:
112.050
[ Flash Point ]:
-30.6±0.0 °C
[ Exact Mass ]:
112.013596
[ PSA ]:
17.07000
[ LogP ]:
0.49
[ Vapour Pressure ]:
865.9±0.0 mmHg at 25°C
[ Index of Refraction ]:
1.287
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
Miscible
MSDS
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H224-H315-H319-H335
[ Precautionary Statements ]:
P210-P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
F+:Highlyflammable;Xi:Irritant;
[ Risk Phrases ]:
R12;R36/37/38
[ Safety Phrases ]:
S16-S26-S29-S33-S36-S7/9-S9-S37/39
[ RIDADR ]:
UN 1993 3/PG 1
[ WGK Germany ]:
3
[ Packaging Group ]:
I
[ Hazard Class ]:
3
[ HS Code ]:
29147090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914700090
[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%
Articles
Hum. Exp. Toxicol. 33(10) , 1051-65, (2014)
The efficacy of methotrexate (MTX), a widely used chemotherapeutic drug, is limited by its gastrointestinal toxicity and the mechanism of which is not clear. The present study investigates the possibl...
Concise synthesis of enantiopure alpha-trifluoromethyl alanines, diamines, and amino alcohols via the Strecker-type reaction.J. Org. Chem. 71 , 7075, (2006)
Diastereomerically pure alpha-trifluoromethyl alpha-amino nitriles obtained by Strecker-type reactions from chiral CF3 imines and iminium proved to be very attractive versatile intermediates for the s...
Synthesis , 251, (2007)