2,2,3,3,3-Pentafluoro-1-propanol

Names

[ CAS No. ]:
422-05-9

[ Name ]:
2,2,3,3,3-Pentafluoro-1-propanol

[Synonym ]:
1H,1H-Pentafluoro-1-propanol
EINECS 207-012-7
1-Propanol, 2,2,3,3,3-pentafluoro-
2,2,3,3,3-Pentafluoro-1-propanol
2,2,3,3,3-Pentafluoropropan-1-ol
MFCD00004673

Biological Activity

[Description]:

2,2,3,3,3-Pentafluoropropan-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

2,2,3,3,3-五氟-1-丙醇用作医药中间体。可用于农药、医药、染料等领域。

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
80.4±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃H₃F₅O

[ Molecular Weight ]:
150.05

[ Flash Point ]:
11.6±25.9 °C

[ Exact Mass ]:
150.010406

[ PSA ]:
20.23000

[ LogP ]:
1.23

[ Vapour Pressure ]:
56.6±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.283

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB8800000

CHEMICAL NAME :: 1-Propanol, 2,2,3,3,3-pentafluoro-

CAS REGISTRY NUMBER :: 422-05-9

BEILSTEIN REFERENCE NO. :: 1743133

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C3-H3-F5-O

MOLECULAR WEIGHT :: 150.06

WISWESSER LINE NOTATION :: Q1XFFXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2250 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes

REFERENCE :: JOCMA7 Journal of Occupational Medicine. (Chicago, IL) V.1-9, 1957-67. For publisher information, see:JJOMDZ Volume(issue)/page/year: 4,262,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 18(3),48,1974

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 gm/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 18(3),48,1974

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 18(3),48,1974

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R10;R20;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39-S16

[ RIDADR ]:
1987

[ WGK Germany ]:
3

[ RTECS ]:
UB8800000

[ HS Code ]:
2905590090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2905590090

[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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