10H-Pyrido(2,3-b)pyrimido(4,5-e)(1,4)thiazine-2,4-diamine, 7-methoxy-
Names
[ CAS No. ]:
42362-20-9
[ Name ]:
10H-Pyrido(2,3-b)pyrimido(4,5-e)(1,4)thiazine-2,4-diamine, 7-methoxy-
[Synonym ]:
2,4-Diamino-7-methoxy-1,3,6-triazaphenothiazin
Chemical & Physical Properties
[ Density]:
1.544g/cm3
[ Boiling Point ]:
609.2ºC at 760 mmHg
[ Molecular Formula ]:
C10H10N6OS
[ Molecular Weight ]:
262.29100
[ Flash Point ]:
322.2ºC
[ Exact Mass ]:
262.06400
[ PSA ]:
140.50000
[ LogP ]:
1.27270
[ Index of Refraction ]:
1.763
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UV1173150
- CHEMICAL NAME :
- 10H-Pyrido(2,3-b)pyrimido(4,5-e)(1,4)thiazine-2,4-dia mine, 7-methoxy-
- CAS REGISTRY NUMBER :
- 42362-20-9
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C10-H10-N6-O-S
- MOLECULAR WEIGHT :
- 262.32
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 12,249,1977