1-Methyl-2-nitroguanidine

Names

[ Name ]:
1-Methyl-2-nitroguanidine

[Synonym ]:
WNMYZUN1
WNMYUM&M1
1-Methyl-2-nitroguanidine
1-Methyl-3-nitroguanidine
Guanidine, N-methyl-N'-nitro-
N-Methyl-N'-nitroguanidine
2-methyl-1-nitroguanidine
MFCD00024167
N-Methyl-N"-nitroguanidine

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
177.3±23.0 °C at 760 mmHg

[ Melting Point ]:
153-155 °C(lit.)

[ Molecular Formula ]:
C₂H₆N₄O₂

[ Molecular Weight ]:
118.095

[ Flash Point ]:
61.0±22.6 °C

[ Exact Mass ]:
118.049072

[ PSA ]:
93.73000

[ LogP ]:
-0.98

[ Vapour Pressure ]:
1.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.588

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MF4125000

CHEMICAL NAME :: Guanidine, 1-methyl-3-nitro-

CAS REGISTRY NUMBER :: 4245-76-5

LAST UPDATED :: 199412

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C2-H6-N4-O2

MOLECULAR WEIGHT :: 118.12

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 3300 mg/L

REFERENCE :: GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year: 27,95,1981

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H228-H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P210-P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
F: Flammable;Xn: Harmful;

[ Risk Phrases ]:
R11;R20/21/22;R36/37/38

[ Safety Phrases ]:
S16-S26-S36/37/39-S48

[ RIDADR ]:
UN 1325 4.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
MF4200000

[ Packaging Group ]:
III

[ Hazard Class ]:
4.1

[ HS Code ]:
2925290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Development of immunoassay based on monoclonal antibody reacted with the neonicotinoid insecticides clothianidin and dinotefuran.

Sensors (Basel.) 12(11) , 15858-72, (2012)

Enzyme-linked immunosorbent assay (ELISA) based on a monoclonal antibody (MoAb) was developed for the neonicotinoid insecticide clothianidin. A new clothianidin hapten (3-[5-(3-methyl-2-nitroguanidino...

Multiple-endpoint mutagenesis with Chinese hamster ovary (CHO) cells: evaluation with eight carcinogenic and non-carcinogenic compounds.

Mol. Toxicol. 1(2-3) , 217-34, (1987)

Previously, we have shown that Chinese hamster ovary (CHO) cells are useful for quantifying chemical-induced gene mutations. We have defined the conditions of a Multiplex CHO System which permits dete...

Hydroxyl free radical production by the reaction of N-methyl-N'-nitro-N-nitrosoguanidine with hydrogen peroxide without exposure to light.

Biochem. Cell Biol. 70(3-4) , 262-8, (1992)

We examined hydroxyl free radical (.OH) production in the mixture of H2O2 and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) without exposure to light using the electron spin resonance spin-trapping tech...