tert-Butyl carbamate

Names

[ Name ]:
tert-Butyl carbamate

[Synonym ]:
carbamic acid 1,1-dimethylethyl ester
BOC-AMIDE
tert-butyloxycarbonylamine
2-Methyl-2-propanyl carbamate
T-BUTYL CARBAMATE
EINECS 224-209-3
Carbamic Acid tert-Butyl Ester
BOC-NH2
MFCD00007962
tert-Butyl carbamate
tert-Butylcarbamat
tert-Butoxycarbonylamine
tert-Butylcarbamate
N-T-BUTOXYCARBONYL AMIDE
Carbamic acid, 1,1-dimethylethyl ester
N-t-butoxycarbonylamine
t-butoxycarbonylamine

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
196.0±9.0 °C at 760 mmHg

[ Melting Point ]:
105-108 °C(lit.)

[ Molecular Formula ]:
C₅H₁₁NO₂

[ Molecular Weight ]:
117.146

[ Flash Point ]:
82.4±15.0 °C

[ Exact Mass ]:
117.078979

[ PSA ]:
52.32000

[ LogP ]:
0.55

[ Vapour Pressure ]:
0.4±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.429

[ Storage condition ]:
Room temperature.

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

One-Pot Three-Component Synthesis of Tetrasubstituted NH Pyrroles from Secondary Propargylic Alcohols, 1, 3-Dicarbonyl Compounds and tert-Butyl Carbamate. Cadierno V, et al.

J. Heterocycl. Chem. 47(1) , 233-36, (2010)

Pd-catalyzed amidation of aryl (Het) halides with< i> tert</i>-butyl carbamate. Qin L, et al.

Tetrahedron Lett. 51(33) , 4446-48, (2010)

Room-temperature Pd-catalyzed amidation of aryl bromides using tert-butyl carbamate.

J. Org. Chem. 74(12) , 4634-7, (2009)

The scope of Pd-catalyzed synthesis of N-Boc-protected anilines from aryl bromides and commercially available tert-butyl carbamate is described. For the first time, this process can be conducted at ro...