1,3-Benzodioxolylbutanamine
Names
[ CAS No. ]:
42542-07-4
[ Name ]:
1,3-Benzodioxolylbutanamine
[Synonym ]:
Benzodioxolylbutanamine
UNII:CM58WOT28Y
1,3-Benzodioxolylbutanamine
(3,4-Methylenedioxyphenyl)-2-butanamine
3,4-methylenedioxy-α-ethylphenethylamine
1-(1,3-benzodioxol-5-yl)butan-2-amine
α-Ethyl-1,3-benzodioxole-5-ethanamine
1-(1,3-benzodioxol-5-yl)butan-2-amine,hydrochloride
1-(1,3-Benzodioxol-5-yl)-2-butanamine
1,3-Benzodioxole-5-ethanamine, α-ethyl-
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
297.3±9.0 °C at 760 mmHg
[ Molecular Formula ]:
C11H15NO2
[ Molecular Weight ]:
193.242
[ Flash Point ]:
145.5±26.0 °C
[ Exact Mass ]:
193.110275
[ PSA ]:
44.48000
[ LogP ]:
2.20
[ Appearance of Characters ]:
white
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.555
[ Storage condition ]:
?20°C
[ Water Solubility ]:
H2O: soluble
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SH6815000
- CHEMICAL NAME :
- Phenethylamine, alpha-ethyl-3,4-methylenedioxy-, hydrochloride
- CAS REGISTRY NUMBER :
- 42542-07-4
- LAST UPDATED :
- 197901
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C11-H15-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 229.73
- WISWESSER LINE NOTATION :
- T56 BO DO CHJ G1YZ2 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 95 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 82 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 16 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy) Gastrointestinal - nausea or vomiting
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 88 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H332
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn,T,F
[ Risk Phrases ]:
20/21/22-39/23/24/25-23/24/25-11
[ Safety Phrases ]:
36-45-36/37-16-7
[ RIDADR ]:
UN 2811 6.1 / PGII
Articles
BMC Genomics 16 , 151, (2015)
Leishmania use exosomes to communicate with their mammalian hosts and these secreted vesicles appear to contribute to pathogenesis by delivering protein virulence factors to macrophages. In other euka...
Slow and steady cell shrinkage reduces osmotic stress in bovine and murine oocyte and zygote vitrification.Hum. Reprod. 30(1) , 37-45, (2014)
Does the use of a new cryoprotectant agent (CPA) exchange protocol designed to minimize osmotic stress improve oocyte or zygote vitrification by reducing sublethal cryodamage?The use of a new CPA exch...
Wear particles derived from metal hip implants induce the generation of multinucleated giant cells in a 3-dimensional peripheral tissue-equivalent model.PLoS ONE 10(4) , e0124389, (2015)
Multinucleate giant cells (MGCs) are formed by the fusion of 5 to 15 monocytes or macrophages. MGCs can be generated by hip implants at the site where the metal surface of the device is in close conta...