PF-63
Names
[ CAS No. ]:
4267-47-4
[ Name ]:
PF-63
[Synonym ]:
3-Piperidinomethyl-rifamycin SV
3-(piperidin-1-yl-methyl)aniline
3-(Piperidylmethyl)phenylamine
[3-(piperidin-1-ylmethyl)phenyl]amine
3-(piperidinomethyl)benzenamine
3-piperidinomethyl-aniline
3-Piperidinomethyl-anilin
Chemical & Physical Properties
[ Density]:
1.33g/cm3
[ Boiling Point ]:
899.9ºC at 760 mmHg
[ Molecular Formula ]:
C43H58N2O12
[ Molecular Weight ]:
794.92700
[ Flash Point ]:
498.1ºC
[ Exact Mass ]:
794.39900
[ PSA ]:
204.55000
[ LogP ]:
5.81590
[ Index of Refraction ]:
1.631
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KD1920900
- CHEMICAL NAME :
- 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy -8-(piperidinomethyl) -, 21-acetate
- CAS REGISTRY NUMBER :
- 4267-47-4
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C43-H58-N2-O12
- MOLECULAR WEIGHT :
- 795.03
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 12,155,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 183 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,531,1977