4-AMINOFLUORENONE

Names

[ Name ]:
4-AMINOFLUORENONE

[Synonym ]:
FLUOREN-9-ONE,4-AMINO
4-amino-fluoren-9-one
EINECS 224-257-5
4-Amino-fluoren-9-on
4-Amino-9H-fluoren-9-one
MFCD00001146
4-Amino-9-fluorenone
9H-Fluoren-9-one,4-amino
4-aminofluorene-9-one
4-Amino-fluorenone

Chemical & Physical Properties

[ Density]:
1.327g/cm3

[ Boiling Point ]:
426.4ºC at 760 mmHg

[ Melting Point ]:
138-140ºC(lit.)

[ Molecular Formula ]:
C₁₃H₉NO

[ Molecular Weight ]:
195.21700

[ Flash Point ]:
211.7ºC

[ Exact Mass ]:
195.06800

[ PSA ]:
43.09000

[ LogP ]:
3.06140

[ Index of Refraction ]:
1.72

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LL8980300

CHEMICAL NAME :: Fluoren-9-one, 4-amino-

CAS REGISTRY NUMBER :: 4269-15-2

BEILSTEIN REFERENCE NO. :: 2804575

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C13-H9-N-O

MOLECULAR WEIGHT :: 195.23

WISWESSER LINE NOTATION :: L B656 HVJ CZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 5 umol/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,11,1981

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26;S37/S39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
LL8980300

[ HS Code ]:
2922399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922399090

[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Structure-activity relationships and optimisation of the selective MDR modulator 2-(3,4-dimethoxyphenyl)-5-(9-fluorenylamino)-2-(methylethyl) pentanenitrile and its N-methyl derivative.

Bioorg. Med. Chem. 9(10) , 2673-82, (2001)

Several ring-substituted derivatives of previously studied MDR inhibitors 2-(3,4-dimethoxyphenyl)-5-(9-fluorenylamino)-2-(methylethyl)pentanenitrile and 2-(3,4-dimethoxyphenyl)-5-[(9-fluorenyl)-N-meth...

Particle beam LC/MS screening of polar compounds of contaminated ground water samples from a former gas plant. Edler BC, et al.

Fresenius J. Anal. Chem. 359(3) , 288-292, (1997)