tert-Butyl methyl malonate

Names

[ Name ]:
tert-Butyl methyl malonate

[Synonym ]:
Propanedioic acid, 1,1-dimethylethyl methyl ester
tert-butyl methylmalonate
EINECS 255-919-1
MFCD00042856
3-O-tert-butyl 1-O-methyl propanedioate
Methyl 2-methyl-2-propanyl malonate
tert.-Butyl methyl malonate
tert-Butyl methyl malonate

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
197.7±0.0 °C at 760 mmHg

[ Melting Point ]:
-10ºC

[ Molecular Formula ]:
C₈H₁₄O₄

[ Molecular Weight ]:
174.194

[ Flash Point ]:
79.4±0.0 °C

[ Exact Mass ]:
174.089203

[ PSA ]:
52.60000

[ LogP ]:
0.87

[ Appearance of Characters ]:
Liquid | Clear colorless to slightly yellow

[ Vapour Pressure ]:
0.4±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.422

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Stereospecific Pd(O)-catalyzed malonate additions to allylic hydroxy phosphonate derivatives: a formal synthesis of (-)-enterolactone.

J. Org. Chem. 69(8) , 2859-62, (2004)

A combination of cross-metathesis and malonate addition was applied to a formal synthesis of the mammalian lignan enterolactone 5. The cross-metathesis of alkene 6 and phosphonate 3a gave the substitu...