2,2,2-Trifluoroacetophenone

Names

[ CAS No. ]:
434-45-7

[ Name ]:
2,2,2-Trifluoroacetophenone

[Synonym ]:
FXFFVR
2,2,2-Trifluoro-1-phenylethanone
TRIFLUOROACETYLBENZENE
Acetophenone, 2,2,2-trifluoro- (8CI)
Ethanone, 2,2,2-trifluoro-1-phenyl-
alpha,alpha,alpha-Trifluoroacetophenone
trifluoromethyl phenyl ketone
2,2,2-trifluroacetophenone
2,2,2-Trifluoro-1-phenyl-ethanone
2,2,2-Trifluoroacetophenone
EINECS 207-103-1
2,2,2-trifluoro-1-phenylethan-1-one
α,α,α-Trifluoroacetophenone
MFCD00000420
Phenyl trifluoromethyl ketone
trifluoromethylphenyl ketone
A,A,A-TRIFLUOROACETOPHENONE
Acetophenone, 2,2,2-trifluoro-
2,2,2-trifluoro-1-phenylethanon

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
165.5±0.0 °C at 760 mmHg

[ Melting Point ]:
-40 °C

[ Molecular Formula ]:
C₈H₅F₃O

[ Molecular Weight ]:
174.120

[ Flash Point ]:
41.7±0.0 °C

[ Exact Mass ]:
174.029251

[ PSA ]:
17.07000

[ LogP ]:
2.15

[ Vapour Pressure ]:
1.9±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.448

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
PRACTICALLY INSOLUBLE

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R10;R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39-S16

[ RIDADR ]:
UN 1224 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29147090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

3-Trifluoromethyl-3-phenyldiazirine. A new carbene generating group for photolabeling reagents.

J. Biol. Chem. 255(8) , 3313-8, (1980)

The synthesis of 3-trifluoromethyl-3-phenyldiazirine (TPD) is reported in an overall yield of 60% based on 2,2,2-trifluoroacetophenone as starting material. TPD is rapidly photolyzed on irradiation ne...

Asymmetric Reductions. IV. The Action of the Grignard Reagent from (+)-2-Methylbutyl Chloride on 2, 2, 2-Trifluoroacetophenone. Mosher HS, et al.

J. Am. Chem. Soc. 78(17) , 4374-4376, (1956)

Synthesis and gas transport properties of new aromatic 3F polymers. Guzman-Gutierrez MT, et al.

J. Memb. Sci. 323(2) , 379-385, (2008)