4-Butoxyanilin

Names

[ Name ]:
4-Butoxyanilin

[Synonym ]:
4-Butyloxybenzenamine
4-Butoxyanilin
MFCD00007866
4-Butoxyaniline
Benzenamine, 4-butoxy-
p-Butoxyaniline
EINECS 224-402-2

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
278.0±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₅NO

[ Molecular Weight ]:
165.232

[ Flash Point ]:
123.6±13.1 °C

[ Exact Mass ]:
165.115356

[ PSA ]:
35.25000

[ LogP ]:
2.34

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.530

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BW9420000

CHEMICAL NAME :: Aniline, p-butoxy-

CAS REGISTRY NUMBER :: 4344-55-2

BEILSTEIN REFERENCE NO. :: 2084421

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H15-N-O

MOLECULAR WEIGHT :: 165.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 89,153,1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 52,215,1956

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S28-S36/37/39-S45

[ RIDADR ]:
2810

[ WGK Germany ]:
3

[ RTECS ]:
BW9420000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors.

J. Med. Chem. 52 , 5044-57, (2009)

Following a ligand-based drug design approach, a potent mixed formyl peptide receptor 1 (FPR1) and formyl peptide receptor-like 1 (FPRL1) agonist (14a) and a potent and specific FPRL1 agonist (14x) we...

Alkali metal cation cooperative anion recognition by heteroditopic bis (calix [4] arene) rhenium (I) bipyridyl and ferrocene receptor molecules. Cooper JB, et al.

J. Chem. Soc., Dalton Trans. 16 , 2721-2728, (2000)

Low-Pressure Hydrogenation of Alkoxyanilines with Noble Metal Catalysts. Freifelder M, et al.

J. Org. Chem. 30(7) , 2485-86, (1965)