5a-androstane

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
336.0±9.0 °C at 760 mmHg

[ Melting Point ]:
78-82 °C(lit.)

[ Molecular Formula ]:
C₁₉H₃₂

[ Molecular Weight ]:
260.457

[ Flash Point ]:
145.9±12.3 °C

[ Exact Mass ]:
260.250397

[ LogP ]:
8.42

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.508

[ Storage condition ]:
-20℃

Click to get detail MSDS

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335-H336-H351-H373

[ Precautionary Statements ]:
P261-P281-P305 + P351 + P338

[ Target Organs ]:
Blood, Central nervous system, Liver

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
45-23/24/25-36/37/38-43-63

[ Safety Phrases ]:
S53-S23-S24/25-S36/37

[ RIDADR ]:
UN 1593 6.1/PG 3

[ WGK Germany ]:
3

Click to get detail synthetic route

Precursor

DownStream

Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.

J. Med. Chem. 52 , 7488-502, (2009)

17beta-Hydroxysteroid dehydrogenase type 7 (17beta-HSD7) catalyzes the reduction of estrone (E(1)) into estradiol (E(2)) and of dihydrotestosterone (DHT) into 5alpha-androstane-3beta,17beta-diol (3bet...

Novel and efficient synthesis and antifungal evaluation of 2,3-functionalized cholestane and androstane derivatives

Bioorg. Med. Chem. Lett. 20 , 7372-5, (2010)

Synthetic modifications of cholesterol and other traditional steroid molecules have become a promising area for the exploration and development of novel antifungal agents, especially with respect to t...

[Bioconversion of C19- and C21-steroids with parent and mutant strains of Curvularia lunata].

Prikl. Biokhim. Mikrobiol. 46(2) , 212-20, (2010)

Regio- and stereospecificity of microbial hydroxylation was studied at the transformation of 3-keto-4-ene steroids of androstane and pregnane series by the filamentous fungus of Curvularia lunata VKMF...

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