LDN-109657

Names

[ Name ]:
LDN-109657

Biological Activity

[Description]:

LDN-109657 is a novel SMN2 modulator that increase SMN protein levels in 3813 fibroblasts by twofold at 370 nM.

[References]

References 1. Cherry JJ, et al. EMBO Mol Med. 2013 Jul;5(7):1103-18. 2. Cherry JJ, et al. J Biomol Screen. 2012 Apr;17(4):481-95. View Related Products by Target SMN2 Modulator

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₀N₂O₃S

[ Molecular Weight ]:
344.429

Related Compounds

ldn-0096812
LDN-0088050
LDN-192960 2HCl
LDN 214117
LDN-211904
LDN-211904
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
2-(1-{[1,3]thiazolo[4,5-c]pyridin-2-yl}azetidin-3-yl)-2H-1,2,3-triazole
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
2,2,3,3,4,4-Hexafluoro-5-naphthalen-1-yl-5-oxo-pentanoic acid
tert-Butyl-DL-alanine