Carboxyethyl-γ-aminobutyric acid

Names

[ CAS No. ]:
4386-03-2

[ Name ]:
Carboxyethyl-γ-aminobutyric acid

[Synonym ]:
4-(2-carboxyethylamino)butanoic acid

Chemical & Physical Properties

[ Density]:
1.232g/cm3

[ Boiling Point ]:
409.2ºC at 760mmHg

[ Molecular Formula ]:
C₇H₁₃NO₄

[ Molecular Weight ]:
175.18200

[ Flash Point ]:
201.3ºC

[ Exact Mass ]:
175.08400

[ PSA ]:
86.63000

[ LogP ]:
0.30640

[ Index of Refraction ]:
1.491

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EK7730000

CHEMICAL NAME :: Butanoic acid, 4-((2-carboxyethyl)amino)-

CAS REGISTRY NUMBER :: 4386-03-2

BEILSTEIN REFERENCE NO. :: 1774240

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H13-N-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 877 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJBIAC Italian Journal of Biochemistry. (I1 Pensiero Scientifico Editore, Via Panama 48, I-00198 Rome, Italy) V.1- 1957- Volume(issue)/page/year: 33,31A,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 783 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJBIAC Italian Journal of Biochemistry. (I1 Pensiero Scientifico Editore, Via Panama 48, I-00198 Rome, Italy) V.1- 1957- Volume(issue)/page/year: 33,31A,1984

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
EK7730000

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Carboxyethyl gamma-aminobutyric acid, a polyamine derivative molecule with a growth effect on hybridomas.

J. Immunol. Methods 77 , 229, (1985)

An increased proliferation of hybridomas is induced by a polyamine derivative molecule, CEGABA (carboxyethyl gamma-aminobutyric acid). The effects of CEGABA and CR-ECGS (endothelial cell growth supple...

Experimental study on central effects of carboxyethyl-gamma-aminobutyric acid (CEGABA).

Farmaco. Sci. 43(4) , 363-72, (1988)

The central effects of carboxyethyl-gamma-aminobutyric acid (CEGABA) have been studied both in rabbits and in the guinea pig myoclonus model. This drug caused EEG synchronization and behavioural sedat...

Identification of N-carboxyethyl gamma-aminobutyric acid in bovine brain and human cerebrospinal fluid.

Neurosci. Lett. 77(3) , 308-10, (1987)

The di-carboxylated derivative of spermidine, N-carboxyethyl gamma-aminobutyric acid (CEGABA) has been identified in bovine brain and human cerebrospinal fluid by HPLC. This discovery strongly suggest...