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4,7,10,13,16-Pentaoxanonadecanedioic Acid

Names

[ CAS No. ]:
439114-13-3

[ Name ]:
4,7,10,13,16-Pentaoxanonadecanedioic Acid

[Synonym ]:
Bis-PEG5-acid
4,7,10,13,16-PENTAOXANONADECANE-1,19-DIOIC ACID
4,7,10,13,16-Pentaoxanonadecanedioic Acid
bis-dPEG6-acid
AmbotzPEG1430

Biological Activity

[Description]:

Bis-PEG5-acid (PROTAC Linker 36) is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. Bis-PEG5-acid (PROTAC Linker 36) can be used in the synthesis of the CP5V. CP5V is a PROTAC, and specifically degrades Cdc20[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

PEGs


[References]

[1]. Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.

Chemical & Physical Properties

[ Density]:
1.205±0.06 g/cm3

[ Molecular Formula ]:
C14H26O9

[ Molecular Weight ]:
338.35100

[ Exact Mass ]:
338.15800

[ PSA ]:
120.75000

[ LogP ]:
0.01880

[ Water Solubility ]:
Freely soluble (924 g/L) (25 ºC)

Safety Information

[ Hazard Codes ]:
Xn

Precursor & DownStream


Related Compounds