2,5-bis(bis-(2-chloroethyl)aminomethyl) hydroquinone
Names
[ CAS No. ]:
4420-79-5
[ Name ]:
2,5-bis(bis-(2-chloroethyl)aminomethyl) hydroquinone
[Synonym ]:
2,5-Bis-{[bis-(2-chlor-aethyl)-amino]-methyl}-hydrochinon
Hydroquinone mustard
2,5-bis-{[bis-(2-chloro-ethyl)-amino]-methyl}-hydroquinone
Weatherbee mustard
Chemical & Physical Properties
[ Molecular Formula ]:
C16H25Cl5N2O2
[ Molecular Weight ]:
454.64700
[ Exact Mass ]:
452.03600
[ PSA ]:
46.94000
[ LogP ]:
4.45900
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MX4200000
- CHEMICAL NAME :
- Hydroquinone, 2,5-bis((bis(2-chloroethyl)amino)methyl)-
- CAS REGISTRY NUMBER :
- 4420-79-5
- BEILSTEIN REFERENCE NO. :
- 2888141
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C16-H24-Cl4-N2-O2
- MOLECULAR WEIGHT :
- 418.22
- WISWESSER LINE NOTATION :
- G2N2G1R BQ EQ D1N2G2G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD10 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4700 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 17,63,1962
- TYPE OF TEST :
- LD10 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2600 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 17,56,1962
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 900 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes Blood - leukopenia Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 1800 ug/kg
- TOXIC EFFECTS :
- Blood - leukopenia Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 28 mg/kg/4W
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 36,915,1966
Safety Information
[ HS Code ]:
2922299090
Customs
[ HS Code ]: 2922299090
[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%