(2R)-2-Methoxy-3,4-dihydro-2H-pyran
Names
[ CAS No. ]:
4454-05-1
[ Name ]:
(2R)-2-Methoxy-3,4-dihydro-2H-pyran
[Synonym ]:
2-Methoxy-3,4-dihydro-2H-pyran
3,4-Dihydro-2-Methoxy-2H-pyran
MFCD00006560
(2R)-2-Methoxy-3,4-dihydro-2H-pyran
2H-Pyran, 3,4-dihydro-2-methoxy-, (2R)-
EINECS 224-698-3
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
149.3±39.0 °C at 760 mmHg
[ Molecular Formula ]:
C6H10O2
[ Molecular Weight ]:
114.142
[ Flash Point ]:
16.7±0.0 °C
[ Exact Mass ]:
114.068077
[ PSA ]:
18.46000
[ LogP ]:
-0.09
[ Vapour Pressure ]:
5.1±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.451
[ Storage condition ]:
Flammables area
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UP7900000
- CHEMICAL NAME :
- 2H-Pyran, 3,4-dihydro-2-methoxy-
- CAS REGISTRY NUMBER :
- 4454-05-1
- BEILSTEIN REFERENCE NO. :
- 0107274
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C6-H10-O2
- MOLECULAR WEIGHT :
- 114.16
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1410 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8044 ppm/1H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - pleural effusion
- REFERENCE :
- VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 4920 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - dyspnea Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 30,545,1988
Safety Information
[ Hazard Codes ]:
F:Highlyflammable;Xn:Harmful;
[ Risk Phrases ]:
R11;R22
[ Safety Phrases ]:
S9-S33-S16-S36-S26
[ RIDADR ]:
1993
[ RTECS ]:
UP7900000
[ Packaging Group ]:
II
[ Hazard Class ]:
3
[ HS Code ]:
2932999099
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2932999099
[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%