4-Chloro-2-fluorobenzoic acid

Names

[ CAS No. ]:
446-30-0

[ Name ]:
4-Chloro-2-fluorobenzoic acid

[Synonym ]:
EINECS 207-162-3
4-chloro-2-fluoro-benzoic acid
4-Chloro-2-fluorobenzoic acid
2-fluoro-4-chlorobenzoic acid
4-chloro-2-fluorobenzoate
Benzoic acid, 4-chloro-2-fluoro-
QVR DG BF
4-Chlor-2-fluor-benzoesaeure
4-chloro-4-fluorobenzoic acid
MFCD00042468
Benzoic acid,4-chloro-2-fluoro

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
274.7±20.0 °C at 760 mmHg

[ Melting Point ]:
204-208 °C(lit.)

[ Molecular Formula ]:
C₇H₄ClFO₂

[ Molecular Weight ]:
174.557

[ Flash Point ]:
119.9±21.8 °C

[ Exact Mass ]:
173.988388

[ PSA ]:
37.30000

[ LogP ]:
2.17

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.558

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

J. Agric. Food Chem. 43 , 219, (1995)

Helv. Chim. Acta 68 , 1444, (1985)

Selective lithiation/carbonation of polyhalobenzenes: an improved synthesis of furosemide-7-14C. Perry CW, et al.

J. Org. Chem. 43(22) , 4391, (1978)