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2,4-Difluorotoluene

Names

[ CAS No. ]:
452-76-6

[ Name ]:
2,4-Difluorotoluene

[Synonym ]:
Benzene, 2,4-difluoro-1-methyl-
EINECS 207-211-9
2,4-Difluoro-1-methylbenzene
2,4-Difluorotoluene
MFCD00000332
FR CF D1
2,4-Difluoro toluene

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
114.7±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H6F2

[ Molecular Weight ]:
128.119

[ Flash Point ]:
15.0±0.0 °C

[ Exact Mass ]:
128.043762

[ LogP ]:
2.82

[ Vapour Pressure ]:
23.4±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.457

[ Storage condition ]:
Flammables area

MSDS

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225

[ Precautionary Statements ]:
P210

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S16-S29-S33

[ RIDADR ]:
UN 1993 3/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2903999090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

A thymine isostere in the templating position disrupts assembly of the closed DNA polymerase beta ternary complex.

Biochemistry 44(46) , 15230-7, (2005)

The high fidelity of the DNA polymerization process is critically important for the stability of the cellular genome. The role of template and incoming nucleotide base pairing in polymerase fidelity h...

Importance of terminal base pair hydrogen-bonding in 3'-end proofreading by the Klenow fragment of DNA polymerase I.

Biochemistry 39(10) , 2626-32, (2000)

We describe studies aimed at evaluating the physical factors governing the rate of 3'-end proofreading by the Klenow fragment of E. coli DNA polymerase I. Two nonpolar deoxynucleoside isosteres contai...

Nonpolar nucleobase analogs illuminate requirements for site-specific DNA cleavage by vaccinia topoisomerase.

J. Biol. Chem. 281(47) , 35914-21, (2006)

Vaccinia DNA topoisomerase forms a covalent DNA-(3'-phosphotyrosyl)-enzyme intermediate at a specific target site 5'-C(+5)C(+4)C(+3)T(+2)T(+1)p downward arrow N(-1) in duplex DNA. Here we study the ef...


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Related Compounds