Cyclo(-ala-gly)

Names

[ Name ]:
Cyclo(-ala-gly)

[Synonym ]:
3-methyl-piperazine-2,5-dione
2,5-Piperazinedione,3-methyl
Cyclo(-Ala-Gly)
3-Methyl-piperazin-2,5-dion
cyclo(Ala-Gly)
2,5-Piperazinedione,3-methyl-,(S)
cyclo-alanylglycine
Cyclo(alanyl-glycyl)

Biological Activity

[Description]:

Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC50 values range from 9.5 to 18.1 μM[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Chen G, et al. The metabolites of a mangrove endophytic fungus, Penicillium thomi. J Asian Nat Prod Res. 2007 Mar;9(2):159-64.

Chemical & Physical Properties

[ Density]:
1.149g/cm3

[ Boiling Point ]:
495.7ºC at 760 mmHg

[ Melting Point ]:
246-247ºC

[ Molecular Formula ]:
C₅H₈N₂O₂

[ Molecular Weight ]:
128.12900

[ Flash Point ]:
256.9ºC

[ Exact Mass ]:
128.05900

[ PSA ]:
58.20000

[ Index of Refraction ]:
1.452

[ Storage condition ]:
2-8°C

Safety Information

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%