4-Fluorophenylacetyl chloride
Names
[ CAS No. ]:
459-04-1
[ Name ]:
4-Fluorophenylacetyl chloride
[Synonym ]:
MFCD00674181
2-(4-fluorophenyl)acetyl chloride
Chemical & Physical Properties
[ Density]:
1.259
[ Boiling Point ]:
60 °C (8 mmHg)
[ Melting Point ]:
47-48
[ Molecular Formula ]:
C8H6ClFO
[ Molecular Weight ]:
172.58400
[ Flash Point ]:
107 °C
[ Exact Mass ]:
172.00900
[ PSA ]:
17.07000
[ LogP ]:
2.13360
[ Vapour Pressure ]:
0.0884mmHg at 25°C
[ Index of Refraction ]:
1.511-1.513
[ Storage condition ]:
Store at RT.
MSDS
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xi: Irritant;C: Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S45-S36/37/39-S26-S27
[ RIDADR ]:
3265
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
2916399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Chem. Pharm. Bull. 44 , 765, (1996)
In order to find new antiasthmatic and antithrombotic agents, various [[1-aryl(or benzyl)-1-(benzenesulfonamido)methyl]phenyl]alkanoic acid derivatives were synthesized. Evaluation of these compounds ...
Drug Des. Discovery 11 , 115, (1994)
Drug Des. Discovery 9 , 155, (1992)