MJN-228
Names
[ CAS No. ]:
459168-97-9
[ Name ]:
MJN-228
[Synonym ]:
(4-Methyl-1-piperazinyl)(5-nitro-3-phenyl-1H-indol-2-yl)methanone
MJN228
Methanone, (4-methyl-1-piperazinyl)(5-nitro-3-phenyl-1H-indol-2-yl)-
Biological Activity
[Description]:
MJN-228 is a selective ligand for the lipid-binding protein nucleobindin 1 (NUCB1) with IC50 of 3.3 uM (blocks AEA-DA probe labeling of NUCB1); shows no affinity for other arachidonoyl probe-protein interactions in HEK293T cell lysate; a probe used to elucidate the role of NUCB1 in lipid metabolic pathways in cells.
[References]
References 1. Niphakis MJ, et al. Cell. 2015 Jun 18;161(7):1668-80. View Related Products by Target Other Targets
Chemical & Physical Properties
[ Density]:
1.3±0.0 g/cm3
[ Boiling Point ]:
629.8±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C20H20N4O3
[ Molecular Weight ]:
364.398
[ Flash Point ]:
334.7±0.0 °C
[ Exact Mass ]:
364.153534
[ LogP ]:
1.75
[ Vapour Pressure ]:
0.0±0.0 mmHg at 25°C
[ Index of Refraction ]:
1.675