1-acetylaziridine
Names
[ CAS No. ]:
460-07-1
[ Name ]:
1-acetylaziridine
[Synonym ]:
1-Acetylaziridine
N-acetyl aziridine
Acetylethylenimide
N-Acetylethyleneimine
AZIRIDINE,1-ACETYL
1-Acetyl-aziridin
Acetylethylenimine
EINECS 207-301-8
N-Acetylethylenimine
Acetylethyleneimine
Chemical & Physical Properties
[ Density]:
1.126g/cm3
[ Boiling Point ]:
174.2ºC at 760mmHg
[ Molecular Formula ]:
C4H7NO
[ Molecular Weight ]:
85.10450
[ Flash Point ]:
76.2ºC
[ Exact Mass ]:
85.05280
[ PSA ]:
20.08000
[ Vapour Pressure ]:
1.22mmHg at 25°C
[ Index of Refraction ]:
1.494
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CM6300000
- CHEMICAL NAME :
- Aziridine, 1-acetyl-
- CAS REGISTRY NUMBER :
- 460-07-1
- BEILSTEIN REFERENCE NO. :
- 0105879
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C4-H7-N-O
- MOLECULAR WEIGHT :
- 85.12
- WISWESSER LINE NOTATION :
- T3NTJ AV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 78 mg/kg/26W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,306,1954
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg/33W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,306,1954
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 80 mg/kg/16W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Tumorigenic - tumors at site of application
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,306,1954
Safety Information
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%