Codeinone
Names
[ CAS No. ]:
467-13-0
[ Name ]:
Codeinone
[Synonym ]:
hydrocodone
(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
(5α)-3-Methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-one
6-Oxocodeine
EINECS 207-386-1
Morphinan-6-one, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5α)-
dihydrocodeine
6-Codeinone
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
466.9±45.0 °C at 760 mmHg
[ Melting Point ]:
182-183ºC
[ Molecular Formula ]:
C18H19NO3
[ Molecular Weight ]:
297.348
[ Flash Point ]:
236.1±28.7 °C
[ Exact Mass ]:
297.136505
[ PSA ]:
38.77000
[ LogP ]:
1.33
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.657
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QD2169000
- CHEMICAL NAME :
- Morphinan-6-one, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-
- CAS REGISTRY NUMBER :
- 467-13-0
- BEILSTEIN REFERENCE NO. :
- 0094188
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C18-H19-N-O3
- MOLECULAR WEIGHT :
- 297.38
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 11 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16(Suppl),68T,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16(Suppl),68T,1964
Safety Information
[ Risk Phrases ]:
R22
[ RIDADR ]:
UN 2811 6.1 / PGIII