3alpha-amino-5alpha-pregnan-20-one
Names
[ CAS No. ]:
474-45-3
[ Name ]:
3alpha-amino-5alpha-pregnan-20-one
[Synonym ]:
Amafolona [INN-Spanish]
(2beta,3alpha,5alpha)-3-Amino-2-hydroxyandrostan-17-one,hydrochloride
Amafolonum
Amafolona
Amafolone
Amafolonum [INN-Latin]
Chemical & Physical Properties
[ Density]:
1.014g/cm3
[ Boiling Point ]:
419.9ºC at 760mmHg
[ Molecular Formula ]:
C21H35NO
[ Molecular Weight ]:
317.50900
[ Flash Point ]:
207.8ºC
[ Exact Mass ]:
317.27200
[ PSA ]:
43.09000
[ LogP ]:
5.26190
[ Vapour Pressure ]:
2.93E-07mmHg at 25°C
[ Index of Refraction ]:
1.516
[ Storage condition ]:
-20°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU4375000
- CHEMICAL NAME :
- 5-alpha-Pregnan-20-one, 3-alpha-amino-
- CAS REGISTRY NUMBER :
- 474-45-3
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C21-H35-N-O
- MOLECULAR WEIGHT :
- 317.57
- WISWESSER LINE NOTATION :
- L E5 B666TJ A1 E1 FV1 OZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CHDDAT Comptes Rendus des Seances de l'Academie des Sciences, Serie D: Sciences Naturelles. (Paris, France) V.262-291, 1966-80. For publisher information, see CRASEV. Volume(issue)/page/year: 274,2830,1972
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 64 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 18,177,1960
Safety Information
[ Hazard Codes ]:
Xn