tetryl
Names
[ CAS No. ]:
479-45-8
[ Name ]:
tetryl
[Synonym ]:
N-METHYL-N,2,4,6-TETRANITROANILINE
Nitramine
2,4,6-trinitrophenylmethylnitramine
EINECS 207-531-9
2,4,6-trinitrophenyl-N-methylnitramine
N-methyl-N-(2,4,6-trinitrophenyl)nitramide
2,4,6-Tetryl
N-Methyl-N-picrylnitramine
Picrylmethylnitramine
Tetril
Tetralite
N-Picryl-N-methylnitramine
Picrylnitromethylamine
Tetryl
N-2,4,6-tetranitro-N-methylaniline
Chemical & Physical Properties
[ Density]:
1.803g/cm3
[ Boiling Point ]:
503.7ºC at 760mmHg
[ Melting Point ]:
130ºC
[ Molecular Formula ]:
C7H5N5O8
[ Molecular Weight ]:
287.14300
[ Flash Point ]:
258.4ºC
[ Exact Mass ]:
287.01400
[ PSA ]:
186.52000
[ LogP ]:
3.13190
[ Index of Refraction ]:
1.686
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BY6300000
- CHEMICAL NAME :
- Aniline, N-methyl-N,2,4,6-tetranitro-
- CAS REGISTRY NUMBER :
- 479-45-8
- BEILSTEIN REFERENCE NO. :
- 0964788
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 31
- MOLECULAR FORMULA :
- C7-H5-N5-O8
- MOLECULAR WEIGHT :
- 287.17
- WISWESSER LINE NOTATION :
- WNN1&R BNW DNW ENW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Liver - fatty liver degeneration Kidney, Ureter, Bladder - changes in both tubules and glomeruli Kidney, Ureter, Bladder - interstitial nephritis
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5580 mg/kg/90D-C
- TOXIC EFFECTS :
- Blood - other changes Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA
- TYPE OF TEST :
- Gene conversion and mitotic recombination
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- REFERENCE :
- TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 5,11,1980 *** REVIEWS *** ACGIH TLV-TWA 1.5 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1.5 mg/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,255,1971 OSHA PEL (Gen Indu):8H TWA 1.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 1.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 1.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 1.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 1.5 mg/m3 JAN 1993 OEL-BELGIUM:TWA 1.5 mg/m3 JAN 1993 OEL-DENMARK:TWA 1.5 mg/m3;Skin JAN 1993 OEL-FINLAND:TWA 1.5 mg/m3;STEL 3 mg/m3;Skin JAN 1993 OEL-FRANCE:TWA 1.5 mg/m3;Skin JAN 1993 OEL-GERMANY:TWA 1.5 mg/m3;Skin JAN 1993 OEL-THE NETHERLANDS:TWA 15 mg/m3;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 1.5 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 1.5 mg/m3;Skin JAN 1993 OEL-TURKEY:TWA 1.5 mg/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 1.5 mg/m3;STEL 3 mg/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO TETRYL-air:10H TWA 1.5 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H302 + H312 + H332-H319
[ Precautionary Statements ]:
P210-P261-P302 + P352 + P312-P304 + P340 + P312-P337 + P313-P403 + P235
[ Hazard Codes ]:
E,T,F
[ Risk Phrases ]:
2-23/24/25-33-36/37/38-11
[ Safety Phrases ]:
35-45-27-16
[ RIDADR ]:
0208
[ WGK Germany ]:
3
[ Hazard Class ]:
1.1
Synthetic Route
Precursor & DownStream
Precursor
DownStream
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