3-hydroxyestra-1,3,5(10)-trien-17-one hydrogen sulphate

Names

[ CAS No. ]:
481-97-0

[ Name ]:
3-hydroxyestra-1,3,5(10)-trien-17-one hydrogen sulphate

[Synonym ]:
estrone-3-sulfate

Biological Activity

[Description]:

Estrone sulfate is an endogenous metabolite present in Blood that can be used for the research of X-Linked Ichthyosis and Obesity[1][2][3].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[In Vitro]

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

[References]

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.

[2]. Lykkesfeldt G, et al. Abnormal androgen and oestrogen metabolism in men with steroid sulphatase deficiency and recessive X-linked ichthyosis. Clin Endocrinol (Oxf). 1985 Oct;23(4):385-93.

[3]. Brind J, et al. Obese men have elevated plasma levels of estrone sulfate. Int J Obes. 1990 Jun;14(6):483-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₁O₅S-

[ Molecular Weight ]:
349.42100

[ Exact Mass ]:
349.11100

[ PSA ]:
91.88000

[ LogP ]:
4.03160

[ Storage condition ]:
-20°C

3-hydroxyestra-1,3,5(10)-trien-17-one hydrogen sulphate

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds