1,3-dithiolane

Names

[ CAS No. ]:
4829-04-3

[ Name ]:
1,3-dithiolane

[Synonym ]:
1,3-Dithiacyclopentane
1,3-DITHIOLANE
MFCD00041425
[1,3]Dithiolan
1',3'-dithiolane

Chemical & Physical Properties

[ Density]:
1.235

[ Boiling Point ]:
83-84°C 35mm

[ Melting Point ]:
68ºC

[ Molecular Formula ]:
C₃H₆S₂

[ Molecular Weight ]:
106.21000

[ Flash Point ]:
68°C

[ Exact Mass ]:
105.99100

[ PSA ]:
50.60000

[ LogP ]:
1.42390

[ Index of Refraction ]:
1.599

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JP0511000

CHEMICAL NAME :: 1,3-Dithiolane

CAS REGISTRY NUMBER :: 4829-04-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C3-H6-S2

MOLECULAR WEIGHT :: 106.21

WISWESSER LINE NOTATION :: T5S CSTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,235,1982

Safety Information

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
3334

[ RTECS ]:
JP0511000

[ HS Code ]:
2934999090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Cationic cyclization of 2-alkenyl-1,3-dithiolanes: diastereoselective synthesis of trans-decalins.

J. Org. Chem. 76(9) , 3274-85, (2011)

An unprecedented and highly diastereoselective 6-endo-trig cyclization of 2-alkenyl-1,3-dithiolanes has been developed yielding trans-decalins, an important scaffold present in numerous di- and triter...

gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor and pyridinium polyhydrogen fluoride.

Chem. Commun. (Camb.) , 654, (2005)

2,2-diaryl-1,3-dithiolanes, readily obtainable from diaryl ketones, were transformed into the corresponding gem-difluoro compounds using a novel reagent combination involving Selectfluor and pyridiniu...

Alpha-keto amide peptides: a synthetic strategy to resin-bound peptide isosteres for protease inhibitor screening on solid support.

J. Comb. Chem. 6(2) , 181-95, (2004)

A synthetic strategy for the formation of resin-bound internal alpha-keto amide peptides suitable for protease inhibitor screening on solid support is presented. This general approach is based on the ...