4-Hydroxypyrazole
Names
Chemical & Physical Properties
[ Density]:
1.415g/cm3
[ Boiling Point ]:
326.1ºC at 760mmHg
[ Molecular Formula ]:
C3H4N2O
[ Molecular Weight ]:
84.07670
[ Flash Point ]:
151ºC
[ Exact Mass ]:
84.03240
[ PSA ]:
48.91000
[ LogP ]:
0.11530
[ Index of Refraction ]:
1.612
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UR0150000
- CHEMICAL NAME :
- Pyrazol-4-ol
- CAS REGISTRY NUMBER :
- 4843-98-5
- BEILSTEIN REFERENCE NO. :
- 0106311
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C3-H4-N2-O
- MOLECULAR WEIGHT :
- 84.09
- WISWESSER LINE NOTATION :
- T5MNJ DQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 92 mg/kg
- TOXIC EFFECTS :
- Liver - hepatitis (hepatocellular necrosis), zonal
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 48,418,1981 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 336 mg/kg/7D-I
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes Biochemical - Metabolism (Intermediary) - other proteins
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 48,418,1981
Safety Information
[ HS Code ]:
2933199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933199090
[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%